Synthesis and Antimicrobial Activity of Schiff base metal complexes derived from Ampicillin with Vanillin

Authors

  • Subitha. S Women’s Christian College, Nagercoil-629001, India
  • Gnana Glory Kanmoni. V Women’s Christian College, Nagercoil-629001, India
  • Issac Sobana Raj. C Nesamony Memorial Christian College,Marthandam-629165,India

DOI:

https://doi.org/10.37628/jcmm.v5i1.528

Abstract

ABSTRACT: Metal -drug complexes compounds are more popular nowadays due to their greater biological activity than uncompleted legends of some drugs. However various studies have shown that Schiff base derived from biologically active ingredients present in natural materials in its pure form. In this paper K(I), Pb(II), Sr(II), Co(III), and Ba(II) complexes were synthesized from Schiff base derived from ampicillin and vanillin. The ligand and metal complexes have been screened for antimicrobial activity against Bacillus Sp, E-Coli, K-Pneumonia, Staphylococus aureus, Pseudomonas auruginosa and against fungal activities. Result revealed moderate change comparing the ligand.

Author Biographies

  • Subitha. S, Women’s Christian College, Nagercoil-629001, India
    Research Scholar, Department of Chemistry and research
  • Gnana Glory Kanmoni. V, Women’s Christian College, Nagercoil-629001, India
    Department of Chemistry and research
  • Issac Sobana Raj. C, Nesamony Memorial Christian College,Marthandam-629165,India
    Department of Chemistry and research

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Published

2019-07-09

Issue

Vol. 5 No. 1 (2019)

Section

Articles