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“Bridging the Gap: Nanotechnology& Role inTissue Engineering”

Riddhi Bhardwaj

Abstract


The multidisciplinary field of tissue engineering combines biology, engineering, and materials science to repair, replace, or regenerate damaged tissues and organs.  In it, the artificial or substitute tissues are implanted to imitate the operations of the damaged tissues. In the past, attempts were made but weren’t satisfactory. Nanotechnology has the potential to modify biological functions and strengthen the properties of scaffolds. This review emphasizes on the need and impact of nanotechnology in creating precise and biomimetic microenvironments, facilitating enhanced tissue engineering Nanoscale materials, including nanoparticles and nanofibers, offer unique properties that enable precise control over cellular interactions and tissue regeneration.  Scaffolds, cells, and growth factors—three essentials for tissue engineering with nanotechnological. A range of biomimetic materials, which possess certain essential properties to function as a temporary extracellular matrix (ECM) and stimulate superior tissue growth compared to EMC that arises spontaneously, have been employed to create scaffolds that enable tissue regeneration. This review also discusses the imperative for nanotechnology in tissue engineering, detailing its versatile techniques, and highlighting its diverse applications. By using the special qualities of nanomaterials, certain methods provide sophisticated approaches for the development of scaffolds in tissue engineering, resulting in biomimetic platforms for tissue regeneration and cell proliferation. Dressings and scaffolds based on nanotechnology alter the fate and development of stem cells, providing approaches for controlled lineage specification and tissue-specific regeneration.  Additionally, by acting as a barrier against infection and boosting tissue regeneration, it aids in the healing of wounds and bone regeneration and bone regeneration. Overall, this synthesis underscores the pivotal role of nanotechnology in shaping the landscape of tissue engineering and advancing regenerative medicine.

Keywords


Tissue engineering, Nanomaterials, scaffolds, Growth factors, Applications

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References


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DOI: https://doi.org/10.37628/ijn.v9i2.1012

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