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A Review on Applications of Bionanotechnology in Nanomedicine: A Theoretical Analysis of Drug Delivery System

Ayushi Pandey

Abstract


Nanotechnology is one of the most recent innovative disciplines in engineering with substantial benefits especially in nanomedicine. It holds a great potential with its application to create materials and devices within the range of the “nano” metric system. The creation of these vast materials can be applicable in diverse fields of science such as biology bionanotechnology, nanoelectronics, and nanomedicine. This field seeks to combine both engineering and medicine to solve scientific and day-to-day problems. This paper reviews the applications of bionanotechnology in nanomedicine because; it is one of the mostly studied applications of nanotechnology, which is in biomedical sciences. Various areas such as drug development, drug production, drug delivery, and clinical diagnostics are analysed in the paper. The review paper highlights the relevance of nanotechnology as an engineering field which is applicable in the field of biology and medicine.


Keywords


nanotechnology, bionanotechnology, nanobiotechnology, nanomedicine, drugs

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References


M Fakrunddin, Z Hossain,H Afraz. Prospects and applications of nanobiotechnology: a medical perspective. Journal of Nanotechnology, pp. 1–6, 2012.

VS Saji, HC Choe,KWK Yeung. Nanotechnology in biomedical applications—A review. International Journal of Nano and Biomaterials, Vol.3, No.2, pp.119–128, 2010.

J Kawadkar, MK Chauhan,M Maharana. Nanobiotechnology: application of nanotechnology in diagnosis, drug discovery and drug development. Asian Journal of Pharmaceutical and Clinical Research. Vol.4, issue 1.pp.23–25, 2011.

KK Jain. Applications of Nanobiotechnology in Clinical Diagnostics. Oak Ridge Conference, pp. 2002–2008, Aug. 2007.

I Khan, M Khan, MN Umar, and DH Oh. Nanobiotechnology and its applications in drug delivery system: a review. Institute of Engineering and Technology Nanobiotechnology.Vol.9, Iss.6, pp.396–400, June, 2015.

RN Alyautdin, EB Tezikov, P Ramge, DA Kharkevich, DJ Begley, and J Kreuter. Significant entry of tubocurarine into the brain of rats by adsorption to polysorbate 80-coated polybutylcyanoacrylate nanoparticles: an in situ brain perfusion study.1998.

Y Matsumura,H Maeda. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. pp. 6387–6392, 1986.

DF Emerich, CG Thanos. Nanotechnology and medicine. Expert OpinBiolTher, pp. 655–663, 2003.

KS Sahoo,V Labhasetwar. Nanotech approaches to drug delivery and imaging. DDT. 8 (24): pp.1112–1120, 2003.

M Diwan, P Elamanchili, H Lane, A Gainer, J Samuel. Biodegradable nanoparticle mediated antigen delivery to human cord blood derived dendritic cells for induction of primary T cell responses. J Drug Target. pp. 495–507, 2003.

MK Hoggard, A Sanchez, and M Alonso. Nanoparticles as carriers for nasal vaccine delivery. Expert Rev Vaccines. pp. 185–196, 2005.

C Medina, MS Martinez, O Corrigan, and M Radomski. Nanoparticles Pharmacological and toxicological significance. Br J Pharmacol. pp.552–558, 2007.

E Oberdorster. Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass. Environ Health Perspective, pp.1058–1062, 2004.

W Gul, Wu, C Chen, Y Xiao. Nanotechnology in the targeted drug delivery for bone diseases and bone regeneration. International Journal of Nanomedicine, pp. 2305–2317, 2013.

J Silva, AR Fernandes, and P V Baptista. Application of Nanotechnology in Drug Delivery, pp.127–140, 2014.

EL Nissenbaum, AFR Moreno, AZ Wang, R Langer, and OC Farokhzad. Trends in Biotechnology, 26(8): pp.442–447, 2008.

JF Coelho, CP Ferreira, P Alves, R Cordeiro, AC Fonseca, JR Góis, MH Gil. Drug delivery systems: Advanced technologies potentially applicable in personalized treatments. EPMA Journal, pp.164–209, 2010.

CL Stevensona, AJT Santini, and R Langerb. Reservoir-Based Drug Delivery Systems Utilizing Microtechnology. Adv Drug Deliv Rev, 64(14): pp.1590–1602. 2012.

NR Jabir, S Tabrez, GM Ashraf, S Shakil, GA Damanhouri, and MA Kamal. Nanotechnology based approaches in anticancer research. International Journal of Nanomedicine, pp.4391–4408, 2012.

A Patel, K Cholkar, V Agrahari, AK Mitra. Ocular drug delivery systems: An overview. World J Pharmacol, 2(2): pp.47–64, 2013.

S Gelperina, K Kisich, MD Iseman, L Heifets. The Potential Advantages of Nanoparticle Drug Delivery Systems in Chemotherapy of Tuberculosis. American Journal of respiratory and critical care medicine, pp.1487–1490, 2005.

M Sechi. Targeted therapy using nanotechnology: focus on cancer. International Journal of Nanomedicine, pp. 467–483, 2014.

TL Andresen,RH Berg. Current Challenges and Future Directions in Nanomedicine. Department of Nanomedicine and Theranostics, Technical University of Denmark, Denmark, Sept. 2013.

P Satalkar, BS Elger, P Hunziker, D Shaw. Challenges of clinical translation in nanomedicine: A qualitative study. Institute for Biomedical Ethics, University of Basel, Basel, Switzerland, pp.893–900, 2016.

CG Doria, P Baptista. Noble Metal Nanoparticles Applications in Cancer. Journal of Drug Delivery, pp.1–12, Aug. 2011.

World Health Organization: WHO (2018). Cancer. [online] Who.int. Available from https://www.who.int/en/news-room/fact-sheets/detail/cancer [Accessed Jul. 2020].


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