Open Access Open Access  Restricted Access Subscription or Fee Access

Experimental Studies on the Surface-Driven Microfluidic Flow of Dyed Working Liquids in Sudden Expansion Microchannels Fabricated by Polymer

Subhadeep Mukhopadhyay

Abstract


In this experimental work, the sudden expansion microchannels are fabricated by maskless lithography, hot embossing lithography, drilling, direct bonding technique and chip separation technique using own hands-on of author completely. Total 15 individual sudden expansion microchannels are fabricated in this work using polymethylmethacrylate (PMMA) as optically transparent polymer. Effects of channel aspect ratio, surface wettability and liquid viscosity on surface-driven microfluidic flow are experimentally studied in the fabricated sudden expansion microchannels. Variations in diffusion coefficient with respect to channel aspect ratio, surface wettability and liquid viscosity are studied. In future, this experimental work may be useful to investigate the effects of channel aspect ratio, surface wettability and liquid viscosity on nanofluidic flow in sudden expansion nanochannels.

Keywords: Sudden expansion, PMMA, Ethylene glycol, Water, Ethanol, Isopropyl alcohol, Diffusion coefficient    


Full Text:

PDF

References


H. A. Stone, A. D. Stroock, A. Ajdari, “Engineering Flows in Small Devices: Microfluidics Toward a Lab-on-a-Chip”, Annu. Rev. Fluid Mech., Vol. 36 (2004) Pages 381-411.

D. Erickson, D. Li, “Integrated Microfluidic Devices”, Analytica Chimica Acta, Vol. 507 (2004) Pages 11-26.

L. J. Yang, T. J. Yao, Y. C. Tai, “The Marching Velocity of the Capillary Meniscus in a Microchannel”, Journal of Micromechanics and Microengineering, Vol. 14 (2004) Pages 220-225.

S. Bouaidat, O. Hansen, H. Bruus, C. Berendsen, N. K. Bau-Madsen, P. Thomsen, A. Wolff, J. Jonsmann, “Surface-Directed Capillary System; Theory, Experiments and Applications”, Lab on a Chip, Vol. 5 (2005) Pages 827-836.

A. A. Saha, S. K. Mitra, “Effect of Dynamic Contact Angle in a Volume of Fluid (VOF) Model for a Microfluidic Capillary Flow”, Journal of Colloid and Interface Science, Vol. 339 (2009) Pages 461-480.

Y. F. Chen, F. G. Tseng, S. Y. ChangChien, M. H. Chen, R. J. Yu, C. C. Chieng, “Surface Tension Driven Flow for Open Microchannels with Different Turning Angles”, Microfluid Nanofluid, Vol. 5 (2008) Pages 193-203.

H. Becker, L. E. Locascio, “Polymer Microfluidic Devices”, Talanta, Vol. 56 (2002) Pages 267-287.

N. S. Cameron, A. Ott, H. Roberge, T. Veres, “Chemical Force Microscopy for Hot-Embossing Lithography release Layer Characterization”, Soft Matter, Vol. 2 (2006) Pages 553-557.

H. Becker, U. Heim, “Hot Embossing as a Method for the Fabrication of Polymer High Aspect Ratio Structures”, Sensors and Actuators, Vol. 83 (2000) Pages 130-135.

P. Datta, J. Goettert, “Method for Polymer Hot Embossing Process Development”, Microsyst Technol, Vol. 13 (2007) Pages 265-270.

C. W. Tsao, D. L. DeVoe, “Bonding of Thermoplastic Polymer Microfluidics”, Microfluid Nanofluid, Vol. 6 (2009) Pages 1-16.

S. Mukhopadhyay, “Experimental Investigations on the Durability of PMMA Microfluidic Devices Fabricated by Hot Embossing Lithography with Plasma Processing for Bioengineering Applications”, Emerging Trends in Chemical Engineering, Vol. 3, Issue 3 (2016) Pages 1-18.

S. Mukhopadhyay, “Experimental Investigations on the Effects of Channel Aspect Ratio and Surface Wettability to Control the Surface-Driven Capillary Flow of Water in Straight PMMA Microchannels”, Trends in Opto Electro and Optical Communications, Vol. 6, Issue 3 (2016) Pages 1-12.

S. Mukhopadhyay, “Report on the Separation Efficiency with Separation Time in the Microfluidic Lab-on-a-Chip Systems Fabricated by Polymers in this 21st Century of 3rd Millennium”, Journal of Experimental and Applied Mechanics, Vol. 7, Issue 3 (2016) Pages 20-37.

S. Mukhopadhyay, “Experimental Investigations on the Surface-Driven Capillary Flow of Aqueous Microparticle Suspensions in the Microfluidic Laboratory-on-a-Chip Systems”, Surface Review and Letters, Vol. 24 (2017) Page 1750107.

S. Mukhopadhyay, “Experimental Investigations on the Effects of Surface Modifications to Control the Surface-Driven Capillary Flow of Aqueous Working Liquids in the PMMA Microfluidic Devices”, Advanced Science, Engineering and Medicine, Vol. 9 (2017) Pages 959-970.

S. Mukhopadhyay, “Surface-Driven Capillary Flow of Dyed Aqueous Ethanol in Sudden Expansion Microchannels”, Journal of Thermal Engineering and Applications, Vol. 4, Issue 3 (2017) Pages 22-25.

S. Mukhopadhyay, “Recording of Surface-Driven Capillary Flow in Polymer-Based Microfluidic Devices for Bioengineering Applications”, International Journal of Optical Sciences, Vol. 4, Issue 1 (2018) Pages 21-27.

S. Mukhopadhyay, “Passive Capillary Flow of Red Dye in the SU-8 based Glass Microfluidic Devices”, Trends in Mechanical Engineering and Technology, Vol. 7, Issue 3 (2018) Pages 59-61.

S. Mukhopadhyay, “Recording of the Surface-Driven Microfluidic Flow of Aqueous Working Liquids in PMMA Microfluidic Devices”, Emerging Trends in Chemical Engineering, Vol. 5, Issue 3 (2018) Pages 24-31.

S. Mukhopadhyay, J. P. Banerjee, S. S. Roy, S. K. Metya, M. Tweedie, J. A. McLaughlin, “Effects of Surface Properties on Fluid Engineering Generated by the Surface-Driven Capillary Flow of Water in Microfluidic Lab-on-a-Chip Systems for Bioengineering Applications”, Surface Review and Letters, Vol. 24 (2017) Page 1750041.

S. Mukhopadhyay, J. P. Banerjee, A. Mathur, M. Tweedie, J. A. McLaughlin, S. S. Roy, “Experimental Studies of Surface-Driven Capillary Flow in PMMA Microfluidic Devices Prepared by Direct Bonding Technique and Passive Separation of Microparticles in Microfluidic Laboratory-on-a-Chip Systems”, Surface Review and Letters, Vol. 22 (2015) Page 1550050.

S. Mukhopadhyay, “Experimental Investigations on the Interactions between Liquids and Structures to Passively Control the Surface-Driven Capillary Flow in Microfluidic Lab-on-a-Chip Systems to Separate the Microparticles for Bioengineering Applications”, Surface Review and Letters, Vol. 24 (2017) Page 1750075.

R. P. Bharti, D. J. E. Harvie, M. R. Davidson, “Steady Flow of Ionic Liquid through a Cylindrical Microfluidic Contraction-Expansion Pipe: Electroviscous Effects and Pressure Drop”, Chemical Engineering Science, Vol. 63 (2008) Pages 3593-3604.

C. H. Tsai, H. T. Chen, Y. N. Wang, C. H. Lin, L. M. Fu, “Capabilities and Limitations of 2-Dimensional and 3-Dimensional Numerical Methods in Modeling the Fluid Flow in Sudden Expansion Microchannels”, Microfluid Nanofluid, Vol. 3 (2007) Pages 13-18.

A. Jain, L. L. Munn, “Determinants of Leukocyte Margination in Rectangular Microchannels”, PLOS ONE, Vol. 4, Issue 9 (2009) Page e7104.

W. Y. Lee, M. Wong, Y. Zohar, “Microchannels in Series Connected Via a Contraction/Expansion Section”, J. Fluid Mech., Vol. 459 (2002) Pages 187-206.

M. S. N. Oliveira, L. E. Rodd, G. H. McKinley, M. A. Alves, “Simulations of Extensional Flow in Microrheometric Devices”, Microfluid Nanofluid, Vol. 5 (2008) Pages 809-826.

J. S. Park, H. Jung, “Multiorifice Flow Fractionation: Continuous Size-Based Separation of Microspheres Using a Series of Contraction/Expansion Microchannels”, Analytical Chemistry, Vol. 81, No. 20 (2009) Pages 8280-8288.

S. Mukhopadhyay, “Passive Capillary Flow of Aqueous Working Liquids in the PMMA Microchannel Bends”, Journal of Catalyst and Catalysis, Vol. 5, Issue 1 (2018) Pages 21-24.

S. Mukhopadhyay, “Passive Capillary Flow of Aqueous Working Liquids in the PMMA Sudden Expansion Microchannels”, Journal of Modern Chemistry and Chemical Technology, Vol. 9, Issue 1 (2018) Pages 17-20.

S. Mukhopadhyay, “Passive Capillary Flow of Aqueous Working Liquids in the Straight PMMA Microchannels of Rectangular Cross-Sections”, Journal of Petroleum Engineering and Technology, Vol. 8, Issue 2 (2018) Pages 5-8.

S. Mukhopadhyay, “Experimental Demonstration on the Recording of Capillary-Filled Microfluidic Devices Fabricated by Polymeric Material”, International Journal of Polymer Science and Engineering, Vol. 5, Issue 2 (2019) Pages 31-41.

S. Mukhopadhyay, J. P. Banerjee, S. S. Roy, “Effects of Channel Aspect Ratio, Surface Wettability and Liquid Viscosity on Capillary Flow Through PMMA Sudden Expansion Microchannels”, Advanced Science Focus, Vol. 1 (2013) Pages 139-144.

V. Jokinen, S. Franssila, “Capillarity in Microfluidic Channels with Hydrophilic and Hydrophobic Walls”, Microfluid Nanofluid, Vol. 5 (2008) Pages 443-448.

G. Blanco-Gomez, A. Glidle, L. M. Flendrig, J. M. Cooper, “Integration of Low-Power Microfluidic Pumps with Biosensors within a Laboratory-on-a-Chip Device”, Analytical Chemistry, Vol. 81 (2009) Pages 1365-1370.

P. R. Waghmare, S. K. Mitra, “On the Derivation of Pressure Field Distribution at the Entrance of a Rectangular Capillary”, Journal of Fluids Engineering, Vol. 132 (2010) Page 054502.

T. M. Squires, S. R. Quake, “Microfluidics: Fluid Physics at the Nanoliter Scale”, Reviews of Modern Physics, Vol. 77 (2005) Pages 977-1026.

D. Mattia, Y. Gogotsi, “Review: Static and Dynamic Behavior of Liquids inside Carbon Nanotubes”, Microfluid Nanofluid, Vol. 5 (2008) Pages 289-305.

W. Sparreboom, A. V. D. Berg, J. C. T. Eijkel, “Transport in Nanofluidic Systems: A Review of Theory and Applications”, New Journal of Physics, Vol. 12 (2010) Page 015004.

D. Mijatovic, J. C. T. Eijkel, A. V. D. Berg, “Technologies for Nanofluidic Systems: top-down vs. bottom-up ---- A Review”, Lab on a Chip, Vol. 5 (2005) Pages 492-500.

M. Rauscher, S. Dietrich, “Wetting Phenomena in Nanofluidics”, Annual Review of Materials Research, Vol. 38 (2008) Pages 143-172.


Refbacks

  • There are currently no refbacks.