A Review on Nanotoxicology
Keywords:
nanotoxicology, nanoparticles, nanomaterials, nanobiotechnology, composite and constituent materialsAbstract
Nanotoxicology shows a novel and extended area for research in toxicology. It deals with the study and application of the toxicity of Nanomaterials. In nanotoxicological studies, nanomaterials such as gold and silver elements becomes highly active and hence, it is important to know to what extent their properties can pose threat to environment and living beings as well. Nanoparticles play a remarkable rule in toxicity, which is important for toxicologists especially in respiratory diseases. Nanoscience contains several applications in several fields and the use of nanomaterials can be in biomedical research, electronics, composite and constituent materials, and materials sciences, etc. All these applications showed potential interest to several biological processes such as blood, coagulation control etc. and these formed a novel field called nanobiotechnology. This review paper is all about nanotoxicology and their threats to humankind. Interestingly, the smaller the particles size is, it can cause more harm to the inside of the body organs, as they can travel by air easily and cannot be visible to naked eyes; therefore, any internal toxicity of particle surface can be highlighted.References
Borm PJA. 2006. Nanotoxicology.Occup. Environ. Med.
Colvin VL. The potential environmental impact of engineered nanomaterials. Nat Biotechnol. 2003;21:1166–70.
Brumfiel G. Nanotechnology: a little knowledge. Nature. 2003;424:246–8.
Kreyling W, Semmler M, Moller W. Dosimetry and toxicology of ultrafine particles. J Aerosol Med. In press.
Borm PJA, Kreyling W. Toxicological hazards of nanoparticles for drug delivery. Journal of Nanoscience and Nanotechnology. In press
Donaldson K, Borm PJA. Particle paradigms. InhalToxicol. 2000;12(suppl 3):1–6.
Donaldson K, Stone V, Clouter A, et al. Ultrafine particles. Occup Environ Med. 2001;58:211–16.
Tran CL, Buchanan D, Cullen RT, et al. Inhalation of poorly soluble particles. II. Influence of particle surface area on inflammation and clearance. InhalToxicol. 2000;12:1113–26.
Donaldson K, Tran CL. Inflammation caused by particles and fibres. InhalToxicol. 2002;14:5–27.
Kumar R. Umar A. Kumar, G. and Nalwa HS. 2017. Antimicrobial properties of ZnO nanomaterials: A review.Ceramics International.43(5):pp.3940–3961.
Walters C, Pool E, Somerset V. 2016. Nanotoxicology: a review.Toxicology—new aspects to this scientific conundrum. InTech, pp.45–63.
Murdock RC, Braydich-Stolle L, Schrand AM, Schlager JJ, Hussain SM. Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique. Toxicological Sciences. 2008;101(2):239–253. doi:10.1093/toxsci/kfm240.
Walters C, Pool E, Somerset V. Nanotoxicity in aquatic invertebrates. In: Larramendy ML, Soloneski S, editors. Invertebrates—Experimental Models in Toxicity Screening. 1st ed. Croatia: InTech; 2016. p. 13–34. doi:10.5772/61715. Available from: https://www.intechopen.com/books/invertebrates-experimental-models-in-toxicity-screening
Stadtman ER, Berlett BS. Reactive oxygen-mediated protein oxidation in aging and disease. 1997. Chemical Research and Toxicology. 10(5):485–494. doi:10.1021/ tx960133r.
